| Control of Gene Expression
Practice Test |
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1. Bacteria require enzymes _________________________________________.
2. In 1961, Francis Jacob and Jacques Monod proposed
____________________ to explain regulation of gene expression in prokaryotes.
3. An operon consists of __________________ types of
genes that function as a single unit.
4. A/An ________________________________ is a gene that
codes for a repressor protein molecule.
5. A/An ________________________________ is a sequence
of DNA where RNA polymerase attaches when a gene is transcribed.
6. A/An _______________ is a sequence of DNA where repressor
can bind, preventing RNA polymerase from attaching to the promotor.
7. A/An ________________________________ is a gene that
codes enzymes of a metabolic pathway; transcribed as a unit.
8. If E. coli cannot get glucose, but lactose is present,
it makes __________________ to metabolize lactose.
9. The enzymes that code for lactose metabolism are _________________________________.
10. When E. coli is confronted with lactose, lactose
binds to the repressor so that it can’t bind to the ______.
11. In the lac operon model, if the repressor can’t bind
to the operator, the promoter is able to bind to ____.
12. E. coli can tell when there is no glucose available
because ___________________________ attach to the lac promotor.
13. In E. coli, the operons for lactose metabolism are
normally __________________________________.
14. E. coli produces five enzymes to synthesize the amino
acid __________________________________.
15. _________________ control determines which structural
genes are transcribed and rate of transcription.
16. __________________ control occurs in nucleus after
DNA is transcribed and preliminary mRNA forms.
17. _________________ control occurs in cytoplasm after
mRNA leaves nucleus but before protein product.
18. ____________________________ control takes place
in the cytoplasm after protein synthesis.
19. Transcription is controlled by DNA-binding proteins
called ______________________________.
20. _____________________ are always present in cell
and most likely they have to be activated in some way before they bind
to DNA.
21. Ultraviolet radiation from sunlight and tanning has
resulted in increased ________________________.
22. Speed of transport of __________ from nucleus into
cytoplasm affects amount of gene product realized.
23. Some proteins are _________________________________________
active after translation.
24. _______________ have a failure in regulation of genes
coding for products that determine cell division.
25. Cancer cells cycle indefinitely and are "immortal";
while normal cells live through about _______ and die.
26. Cancer cells have abnormal nuclei that are _________
and may have abnormal numbers of chromosomes.
27. In cancer cells, the chromosomes have _______________________________________________.
28. When normal cells come into contact with a neighbor,
they stop dividing; _______________________.
29. Cancerous tumor is a __________________, an abnormal
mass of cells that invades neighboring tissue.
30. A _______________________ is a disorganized mass
of cells, but they do not invade adjacent tissues.
31. Cancer cells undergo ________________________________________.
32. ________________ is formation of new blood vessels;
required to bring nutrients and oxygen to tumor.
33. ________________________________ is the spread of
cancer away from the place of origin.
34. ____________ are environmental agents; _________
increase chances of mutations that lead to cancer.
35. Mutagenic carcinogens include _______________________________,
organic chemicals, and viruses.
36. Gene expression in eukaryotes can produce __________________________________________.
Control of Gene Expression
Notes
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